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Lyprinol®

"Lyprinol® is the most powerful anti-inflammatory marine oil available at present. It is superior to conventional pharmaceuticals, vegetable-based omega-3 oils, and other fish oils."

- Georges M. Halpern, M.D., Ph.D.,
Excerpted from: Lyprinol® A Natural Solution For Arthritis And Other Inflammatory Disorders

Lyprinol® has been shown through clinical research to be an extremely potent anti-inflammatory.

The amount of research conducted on Lyprinol is impressive and quite unique for a dietary supplement. In a 1998 study comparing the effectiveness of Lyprinol stabilized green lipped mussel (Perna canaliculus) with the raw green lipped mussel powder, both forms supported healthy joint function and normal range of motion.†8 The only difference was in speed of action: the Lyprinol extract achieved a more rapid response, demonstrating that the nutritional supplement Miracle form the Sea Lyprinol contains the same key compounds present in the raw mussel.8

To validate the clinical efficacy and safety of stabilized green lipped mussel in supporting healthy joint function and healthy range of motion, sixty participants received Lyprinol at two capsules twice a day. Scores at the four week period demonstrated that 53% of the participants experienced significant support for joint health and range of motion.† At the completion of the eight week treatment period, scores had increased dramatically, demonstrating that 80% of the participants experienced enhanced support of joint function and range of motion.†10 There were no reported adverse events.10

Since many of the currently used anti-inflammatory drugs, in particular the non-steroid anti-inflammatory drugs (NSAID), function via the cyclo-oxygenase pathway, much recent international research and effort has gone into the development of inhibitors of the second major pathway, the lipoxygenase pathway. Research has demonstrated that the extract of New Zealand green-lipped mussel in Lyprinol functions as a 5-lipoxygenase pathway inhibitor.

In recent research, Lyprinol was compared to flaxseed oil, evening primrose oil, salmon oil, and fish oil.

On a dosage per body weight basis, Lyprinol® was demonstrated to be:

100 times more potent than fish oil
125 times more potent than green lipped mussel powder
175 times more potent than evening primrose oil
175 times more potent than salmon oil
200 times more potent than flaxseed in supporting healthy joints†11

Unique among nutritional supplements, Lyprinol shows evidence based nutritional support for healthy joints and bronchial airways.† Ongoing clinical studies have demonstrated Lyprinol to be safe and effective.

There is little doubt that Lyprinol® can provide a potent means of controlling and inhibiting the damage caused by the excesses of the body's inflammatory responses.

Dosing: Initially take 4 softgels per day. 2 in the morning and 2 at night with meals for approximately 3-6 weeks after which the intake may be reduced to 1-2 softgels per day.

The initial dosing period allows allows Lyprinol to maintain a constant presence in your body. After you start seeing and feeling the benefits of Lyprinol, you can reduce your daily dosage to 1 softgel in the morning and 1 softgel in the evening.

Lyprinol, 60 gels Your Price: $29.00 Regular: $43.50

 

References:

1. Highton TC, McArthur AW. Pilot study on the effect of New Zealand green mussel on rheumatoid arthritis. N Z Med J. 1975;81:261-2.

2. Miller TE, Ormrod D. The anti-inflammatory activity of Perna canaliculus (NZ green lipped mussel). N Z Med J. 1980;92:187-93.

3. Sinclair AJ, Murphy KJ, Li D. Marine lipids: overview "news insights and lipid composition of Lyprinol". Allerg Immunol (Paris). 2000;32:261-71.

4. Miller TE, Dodd J, Ormrod DJ, Geddes R. Anti-inflammatory activity of glycogen extracted from Perna canaliculus (NZ green-lipped mussel). Agents Actions. 1993;38 Spec No:C139-42.

5. Murphy KJ, Mann NJ, Sinclair AJ. Fatty acid and sterol composition of frozen and freeze-dried New Zealand Green Lipped Mussel (Perna canaliculus) from three sites in New Zealand. Asia Pac J Clin Nutr. 2003;12:50-60.

6. Halpern GM. Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol). Allerg Immunol (Paris). 2000;32:272-8.

7. United States Patent and Trademark Office Website. McFarlane SJ, Croft JE. Pharmaceutical preparations with gastro-protective action. US Patent 4,455,298. Issued June 19, 1984. Accessed on September 20, 2006. Available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=4,455,298.PN.&OS=PN/4,455,298&RS=PN/4,455,298.

8. Gibon SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus; a randomized trial. Complement Ther Med.1998; 6:122-126.

9. Emelyanov A, Fedoseev G, Krasnoschekova O, Abulimity A, Trendeleva T, Barnes PJ. Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial. Eur Respir J. 2002;20:596-600.

10. Cho SH, Jung YB, Seong SC, et al. Clinical efficacy and safety of Lyprinol, a patented extract from New Zealand green-lipped mussel (Perna Canaliculus) in patients with osteoarthritis of the hip and knee: a multicenter 2-month clinical trial. Allerg Immunol (Paris). 2003;35:212-6.

11. Whitehouse MW, Macrides TA, Kalafatis N, Betts WH, Haynes DR, Broadbent J. Anti-inflammatory activity of a lipid fraction (Lyprinol) from the NZ green-lipped mussel. Inflammopharmacology. 1997;5:237-246.

12. Tenikoff D, Murphy KJ, Le M, Howe PR, Howarth GS. Lyprinol (stabilised lipid extract of New Zealand green-lipped mussel): a potential preventative treatment modality for inflammatory bowel disease. J Gastroenterol. 2005;40:361-5.

13. Whitehouse MW. Call for a trial of Lyprinol, an over-the-counter 5-lipoxygenase inhibitor:comment on the article by Kowal-Bielecka et al. Arthritis Rheum. 2002;46:1977-8.